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Switzerland’s Venture Capital Reality Check: A Biotech Mirage in a Hollowed Ecosystem

This article is an analysis of the SECA Venture Capital 2025 Mid-Year Report.

Switzerland’s venture capital performance in the first half of 2025 appears solid on the surface. Invested capital rose 36% year-on-year to CHF 1.47 billion. Yet beneath this surge lies a fragile reality: deal volume continues to shrink, capital is flowing to a narrowing set of sectors and stages, and investor confidence is riddled with contradictions. The latest Swiss Venture Capital Report, co-published by SECA and Startupticker.ch, reveals not a market in recovery but one grappling with its dependencies and imbalances.

Three forces define the current cycle: overconcentration in biotech, a capital gap for scale-up, and a mismatch between investor optimism and portfolio anxiety. While headlines focus on unicorns and record rounds, the data tells a more precarious story.

Biotech as Lifeline—or Lifeboat?

Sector dominance driven by a few mega-deals

Biotech accounted for CHF 705 million of capital in H1 2025, nearly half of the total raised nationwide. This marks a historic high, powered by a handful of huge rounds. Windward Bio alone brought in CHF 183.1 million. GlycoEra followed with CHF 107.5 million. Both companies are early-stage but backed by highly experienced founding teams and late-stage science pipelines. These deals highlight the country’s unparalleled capacity to translate academic research into investor-grade companies.

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